The following are suggestions that I think will make your trip more enjoyable.

1. Make sure your wife and family members know where to get emergency contact information
2. Make sure your wife and family members have access to the emergency contact list (phone numbers and hotels).
3. Print out the emergency contact list and bring with you.
4. Review the general packing list for any items you may have forgotten.
5. Fill up your bike with gas the DAY BEFORE we leave.
6. Check your tire pressure.
7. Bring a few extra rags to clean your windshield in the morning.
8. For you BMW riders, remember in Europe how Leon added oil to your bike halfway through the trip - you may need a little oil??
9. Bring two pair of riding gloves, cold in the morning, hot the rest of the day.
10. Bring your bike registration and insurance certificates.
11. Trial pack your bike to see if everything fits (two gallon zip lock bags work best).
12. Bring a map (with the route marked on it).
13. Bring sunscreen.
14. It will probably be cool in the mornings and hotTTTTT the rest of the day, make sure you can store your jacket on the bike somewhere (usually a nylon gym bag strapped to the passenger seat works well - storing it loose allows the arms to drag).
15. If you have any electronics (phone, digital camera etc) remember to either bring the charger or extra batteries.
16. If you are worried about your bike being stolen, bring a cable and padlock.
17. Bring a spare ignition key.
18. If you wear contacts, the wind will dry them out, bring spare glasses and contact cleaner.
19. Bring a roll of toilet paper (can you spell emergency?)